ASTASHINE

AstaReal® astaxanthin in ASTASHINE is the most studied brand of astaxanthin in the world for applications such as skin health, anti-aging, muscle endurance, gastric health, vision, eye health and immune function. AstaReal produces superior natural astaxanthin products that are of the highest potency, quality and stability.

Oxidative Stress & Antioxidants

Free Radical Attacks & Oxidation Stress Speed up the Aging Process

Free radicals are unstable, highly reactive molecules that have unpaired electrons. They can be generated naturally
in our bodies by different metabolic activities, enzymatic reactions and exercise. These radicals are usually produced in a scale that the body’s natural antioxidants can handle.

In our day to day lives, we are exposed to free radicals produced by various other sources in the environment around us; for example – pollution, smoking, UV radiation from the sun and the consumption of alcohol. This constant exposure to such a toxic environment creates a significant imbalance between the body´s natural antioxidant capacity and its ability to neutrlize free radicals. The result is a damaging condition called “oxidative stress”.

One of the primary causes of human aging is oxidative stress caused by free radical attacks. They have harmful effects on lipids, proteins, DNA and can cause serious damage to the human body. Oxidative stress has
also been shown to contribute significantly to various inflammatory diseases.

Put simply, antioxidants are molecules that work against the oxidation of the cells. They are stable enough to offer electrons to free radicals and thus help neutralize them. They provide protection against the damaging effects of free radicals.

Astaxanthin is the most powerful antioxidant and anti-inflammatory known to science until this moment. Its power comes from its unique structure that allows it to quench free radicals in the inner and outer layer of the cell membrane unlike other antioxidants.

What Is Astaxanthin?

AstaReal® Natural Astaxanthin in ASTASHINE is from the microalgae Haematococcus pluvialis, is a natural carotenoid that can be found from arctic marine environments, to common fresh water rock pools throughout the world. Astaxanthin is what gives the pink and red color to salmon, shrimp and lobster. In the natural environment, animals depend on their diet to
obtain astaxanthin and other carotenoids since they cannot produce carotenoids themselves. The most abundant source of astaxanthin in nature isHaematococcus pluvialis, which will accumulate astaxanthin in lipid vesicles during periods of nutrient deficiency and environmental stress. Because Haematococcusoften grows in places that are exposed to intense sunlight during its dormant phase, astaxanthin functions to protect the cell nucleus against free radicals generated by UV radiation that would otherwise cause damage to its DNA and peroxidise energy reservoirs.

Natural astaxanthin has a unique molecular structure that makes it literally hundreds of times stronger than any other antioxidant molecule. For this reason, astaxanthin is often called “The King of Antioxidants”.

The Power of Astaxanthin

Why Astaxanthin is Nature´s Most Powerful Anti-Aging Molecule

Purest Antioxidant Molecule because it has no-proxidant activity even when subjected to enormous amount of stress from environmental factors and free radicals.

  • Strongest Singlet-Oxygen Quencher among anti-aging molecules
  • Provides Superior Mitochondria Protection as research shows
  •  that is 1,000 times more effectively than Vitamin E against lipid peroxidation in the mitochondria
  • Synergies and protect our endogenous antioxidants from early degradation
  • Reduces DNA Damage and premature cell death caused by oxidation and plasma C-reactive oxygen
  • Crosses Brain-Retinal Blood Barrier leading to neuro-protective effects and alleviation of eye fatigue.
  • Powerful Anti-Inflammatory – Several in-vitro and in-vivo studies shows that ASX strongly suppressed nuclear translocation of NFkB inflammatory cascade, which are the leading cause of most degenerative diseases.

Clinical Studies

There are over 400 peer reviewed studies on astaxanthin. AstaReal® has been featured in the vast majority of these studies. The clinical database for AstaReal® contains over 50 human studies, including 23 double-blind, placebo-controlled trials, with more than 1,400 participants undergoing treatments lasting from 2 weeks to 6 months. The doses used in these trials ranged from 2 to 45 mg/day. The trials were designed to determine the efficacy, safety, and tolerance of AstaReal® astaxanthin for different doses, treatment periods, study designs, and demographic variables including age, gender, and ethnicity. All studies revealed no adverse effects based on hematological findings, serum chemistry, urinal analysis, and self-report questionnaires.

Role of Astaxanthin in Diabeties

Astaxanthin shows positive effects in a type 2 diabetic and reduces the disease progression by retarding glucose toxicity.

  • Astaxanthin is a more potent antioxidant (ROS) reactive oxygen species which helps in exerting beneficial effect in diabetic conditions such as preservation of β –cell function.
  • It is useful as a part of a nutrigenomic strategy for type-2 Diabetic nephropathy.
  • It helps in preserved pancreas function and insulin sensitivity.
  • Astaxanthin improves reduced kidney damage and diabetic nephropathy
  • .pdf_button       AxClinical Study_Diabetes_JUL30.2010
  • pdf_button       Axstudy_Diabetes_APR07.2008

Astaxanthin in Brain

Natural astaxanthin improves age-related forgetfulness, multitasking, and alertness.It helps in decreasing oxidation of red blood cells, which is linked to prevention of dementia

Astaxanthin enhances capillary blood flow and blood antioxidant quality.

It modulates blood pressure, lowering stroke risk and improves vascular endothelial health.

Helps in development and progression of neurodegenerative conditions, such as Alzheimer’s disease and Parkinson’s disease and to cerebral vascular diseases.

Astaxanthin helps in improving blood flow and increase antioxidant capacity.

pdf_buttonAstaREAL-October2015-brain

Role of Astaxanthin Cardiovascular Disease

  • Astaxanthin helps in increase HDL Cholesterol (High Density Lipoprotein)
  • It helps in increasing plaque stability and reduces blood pressure.
  • It helps in decrease lipid peroxidation and reduction of triglyceride levels.
  • Improves blood lipid profile and reduces oxidative stress.
  • Enhance capillary circulation with improved cardiovascular health.

pdf_button      AstaREAL-October2015-cardio

pdf_button      FujiTechNewsletter_JUN10

Role of Astaxanthin in Gastric Health

It helps in decreasing oxidative stress by astaxanthin’s potent antioxidant property; controlling bacterial infection by shifting the immune response

  • It helps in alleviating dyspeptic symptoms by retarding inflammation.
  • It shows high efficacy in non-ulcer dyspepsia.
  • Astaxanthin improves trends included reduced gastric pain and abdominal pain.
  • Astaxanthin helps in alleviating dyspeptic symptoms by retarding inflammation.
  • Its response exacerbates inflammation and epithelial cell damage due to infections, supplementations with astaxanthin helps in lowering inflammation.

pdf_button      AxClinicalStudy_Gastric_JUL30.2010

Role of Astaxanthin in Hypertension

Astaxanthin enhances vascular resilience.010

Maintains vessel integrity

Restoration of Vessel Dilation and Construction

Reduction of Arterial Blood Pressure.

Helps in inducing vasodilation and therefore decreasing blood pressure.

Astaxanthin is useful in antioxidant therapy to alleviate hypertension.

pdf_button      AxClinical Study_Hypertension_JUL30.2010
pdf_button      Axstudy_Hypertension_MAR28.2007

Role of Astaxanthin in Immune System

Natural asta007xanthin possesses potent anti-inflammatory properties.

Helps in enhancing the capacity of both lymphocytes and phagocytes.

Faster immune response.

Strengthens and balance the immune system.

Protects immune cells against oxidative stress.

Astaxanthin has been significantly decreasing the expression of pro –inflammatory markers and mediators.

pdf_button      AstaREAL-October2015-immune-system (1)
pdf_button      AstaREAL-October2015-immune-system

Role of Astaxanthin in skin

Revitalizes photo aged skin by quenching oxidative stress and inflammation in all skin layers

Reduces the size of wrinkles and improves skin micro texture

Improves elasticity in the skin by strengthening the collagen layer

Helps in increase elasticity, improves visible signs of premature aging and general skin health.

Reduces puffiness and erythema

Helps to increase skin’s ability to resist environmental stripping of skin nutrients

pdf_button      ASD_Skin_AUG052014
pdf_button      AstaREAL-October2015-skin
pdf_button      AxClinicalStudy_Skin_FEB14.2011
pdf_button    FujiTechNewsletter_DEC07_Skin

Role of Astaxanthin in Muscle Endurance

Boosts muscle endurance and recovery.

Lowers lactic acid and fatigue.

Reduces muscle damage and inflammation.

Improves blood flow and the quality of red blood cells.

Enhances fat metabolism by improving mitochondria function.

pdf_button    AstaREAL-October2015-muscle

Role of Astaxanthin in Eye Vision

Improving symptoms linked to Computer Vision Syndrome and eye fatigue.

Improving capillary blood flow.

Reducing inflammation of the ciliary muscle.

Improves accommodation responsiveness, range and resilience.

Improves blood capillary circulation of eyes.

Improves eye fatigue.

pdf_button      ASD_Vision_APR152014
pdf_button      AstaREAL-October2015-vision
pdf_button      Study_Eye_JUL30.2010
pdf_button    Ax-g_Eye_SEP06.2010
pdf_button    Axstudy_Eye_MAR10.2008
pdf_button      Bulletin_Vision_JUN242014
pdf_button      DEC08_IrisCiliaryBodyEye
pdf_button    JAN09_ComputerVisionSyndrome

Role of Astaxanthin in Cancer

Helps to inhibit the enzyme 5-alpha reeducates.

Helps to slower cancer cell growth.

Modulates immune responses against tumor cells.

Reduces tumor growth and inhibits stress- induced suppression of tumor fighting natural killer cells

Blocks rapid cell replication of tumors.

Role of Astaxanthin in detoxification and liver function.

Helps to protect mitochondrial cells against lipid per oxidation.

Helps to induce xenobiotic metabolizing enzymes.

Helps in scavenging of radicals to prevent oxidative damage of liver.

Role of Astaxanthin on Joint Health

Astaxanthin is a important tool in fighting against inflammation in arthritis and joint pains.

Helps to inhibit cycloxygenase enzyme, which cause pain and joint destruction.

Helps to block 5-lipo-oxygenase enzyme which is known to damage joint tissues.

helps to inhibit production of iNOS, which causes inflammation, redness, pain and swelling.