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Oxidative Stress & Antioxidants

Free radical attacks & oxidative stress speed up the aging process

Free radicals are unstable, highly reactive molecules that have unpaired electrons. They can be generated naturally in our bodies by different metabolic activities, enzymatic reactions and exercise. These radicals are usually produced in a scale that the body’s natural antioxidants can handle.

In our day to day lives, we are exposed to free radicals produced by various other sources in the environment around us; for example – pollution, smoking, UV radiation from the sun and the consumption of alcohol. This constant exposure to such a toxic environment creates a significant imbalance between the body´s natural antioxidant capacity and its ability to neutrlize free radicals. The result is a damaging condition called “oxidative stress”.

One of the primary causes of human aging is oxidative stress caused by free radical attacks. They have harmful effects on lipids, proteins, DNA and can cause serious damage to the human body. Oxidative stress has also been shown to contribute significantly to various inflammatory diseases.

Put simply, antioxidants are molecules that work against the oxidation of the cells. They are stable enough to offer electrons to free radicals and thus help neutralize them. They provide protection against the damaging effects of free radicals.

Astaxanthin is the most powerful antioxidant and anti-inflammatory known to science until this moment. Its power comes from its unique structure that allows it to quench free radicals in the inner and outer layer of the cell membrane unlike other antioxidants.

Why Astaxanthin is Nature´s Most Powerful Anti-Aging Molecule

  • Purest Antioxidant Molecule because it has no-proxidant activity even when subjected to enormous amount of stress from environmental factors and free radicals
  • Strongest Singlet-Oxygen Quencher among anti-aging molecules
  • Provides Superior Mitochondria Protection as research shows that is 1,000 times more effectively than Vitamin E against lipid peroxidation in the mitochondria
  • Synergies and protect our endogenous antioxidants from early degradation
  • Reduces DNA Damage and premature cell death caused by oxidation and plasma C-reactive oxygen
  • Crosses Brain-Retinal Blood Barrier leading to neuro-protective effects and alleviation of eye fatigue.
  • Powerful Anti-Inflammatory – Several in-vitro and in-vivo studies shows that ASX strongly suppressed nuclear translocation of NFkB inflammatory cascade, which are the leading cause of most degenerative diseases.




There are over 400 peer reviewed studies on astaxanthin. AstaReal® has been featured in the vast majority of these studies. The clinical database for AstaReal® contains over 50 human studies, including 23 double-blind, placebo-controlled trials, with more than 1,400 participants undergoing treatments lasting from 2 weeks to 6 months. The doses used in these trials ranged from 2 to 45 mg/day. The trials were designed to determine the efficacy, safety, and tolerance of AstaReal® astaxanthin for different doses, treatment periods, study designs, and demographic variables including age, gender, and ethnicity. All studies revealed no adverse effects based on hematological findings, serum chemistry, urinal analysis, and self-report questionnaires.


Role of Astaxanthin in Diabeties

  • Astaxanthin shows positive effects in a type 2 diabetic and reduces the disease progression by retarding glucose toxicity.
  • Astaxanthin is a more potent antioxidant (ROS) reactive oxygen species which helps in exerting beneficial effect in diabetic conditions such as preservation of β –cell function.
  • It is useful as a part of a nutrigenomic strategy for type-2 Diabetic nephropathy.
  • It helps in preserved pancreas function and insulin sensitivity.
  • Astaxanthin improves reduced kidney damage and diabetic nephropathy.


Role of Astaxanthin Cardiovascular Diseases


  • Astaxanthin helps in increase HDL Cholesterol (High Density Lipoprotein)
  • It helps in increasing plaque stability and reduces blood pressure.
  • It helps in decrease lipid peroxidation and reduction of triglyceride levels.
  • Improves blood lipid profile and reduces oxidative stress.
  • Enhance capillary circulation with improved cardiovascular health.





Astaxanthin in Brain


  • Natural astaxanthin improves age-related forgetfulness, multitasking, and alertness.
  • It helps in decreasing oxidation of red blood cells, which is linked to prevention of dementia.
  • Astaxanthin enhances capillary blood flow and blood antioxidant quality.
  • It modulates blood pressure, lowering stroke risk and improves vascular endothelial health
  • Helps in development and progression of neurodegenerative conditions, such as Alzheimer’s disease and Parkinson’s disease and to cerebral vascular diseases.
  • Astaxanthin helps in improving blood flow and increase antioxidant capacity.



Role of Astaxanthin in Gastric Health

  • It helps in decreasing oxidative stress by astaxanthin’s potent antioxidant property; controlling bacterial infection by shifting the immune response
  • It helps in alleviating dyspeptic symptoms by retarding inflammation.
  • It shows high efficacy in non-ulcer dyspepsia.
  • Astaxanthin improves trends included reduced gastric pain and abdominal pain.
  • Astaxanthin helps in alleviating dyspeptic symptoms by retarding inflammation.
  • Its response exacerbates inflammation and epithelial cell damage due to infections, supplementations with astaxanthin helps in lowering inflammation.

Role of Astaxanthin in Hypertension

  • Astaxanthin enhances vascular resilience.
  • Maintains vessel integrity
  • Restoration of Vessel Dilation and Construction
  • Reduction of Arterial Blood Pressure.
  • Helps in inducing vasodilation and therefore decreasing blood pressure.
  • Astaxanthin is useful in antioxidant therapy to alleviate hypertension.


Role of Astaxanthin in Immune

  • Natural astaxanthin possesses potent anti-inflammatory properties.
  • Helps in enhancing the capacity of both lymphocytes and phagocytes.
  • Faster immune response
  • Strengthens and balance the immune system
  • Protects immune cells against oxidative stress
  • Astaxanthin has been significantly decreasing the expression of pro –inflammatory markers and mediators.




Role of Astaxanthin in skin


  • Revitalizes photo aged skin by quenching oxidative stress and inflammation in all skin layers
  • Reduces the size of wrinkles and improves skin micro texture
  • Improves elasticity in the skin by strengthening the collagen layer
  • Helps in increase elasticity, improves visible signs of premature aging and general skin health.
  • Reduces puffiness and erythema
  • Helps to increase skin’s ability to resist environmental stripping of skin nutrients



                                Role of Astaxanthin in muscle endurance

  • Boosts muscle endurance and recovery
  • Lowers lactic acid and fatigue
  • Reduces muscle damage and inflammation
  • Improves blood flow and the quality of red blood cells
  • Enhances fat metabolism by improving mitochondria function


      Role of Astaxanthin in eye vision

  • Improving symptoms linked to Computer Vision Syndrome and eye fatigue
  • Improving capillary blood flow
  • Reducing inflammation of the ciliary muscle
  • Improves accommodation responsiveness, range and resilience.
  • Improves blood capillary circulation of eyes.
  • Improves eye fatigue




Role of astaxanthin in cancer

  • Helps to inhibit the enzyme 5-alpha reeducates
  • Helps to slower cancer cell growth
  • Modulates immune responses against tumor cells
  • Reduces tumor growth and inhibits stress- induced suppression of tumor fighting natural killer cells
  • Blocks rapid cell replication of tumors.


Role of Astaxanthin in detoxification and liver function


  • Helps to protect mitochondrial cells against lipid per oxidation.
  • Helps to induce xenobiotic metabolizing enzymes.
  • Helps in scavenging of radicals to prevent oxidative damage of liver


Role of astaxanthin as a unique cell membrane antioxidant

Helps in bridging the cell membrane with potent protection against free a radical or other oxidative attack by

  • Neutralizing radical species of nitrogen, sulfur or carbon in addition to oxygen.
  • Binds with radicals to form a un reactive adduct
  • Helps reduce per oxidation by preserving the membrane structure
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